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Molecular Diagnostics, Genomics and Epigenetics in Clinical Oncology with a Focus on Breast Cancer

05.03.2021  -  06.03.2021

Rome, Italy

*Third party registration should be used if you are requesting an individual registration for someone who is not you.
Please note that website registration under your name will be needed before registering someone else to this event.


Due to the ongoing Coronavirus (COVID-19) crisis, SPCC have made the difficult decision, together with the chairs and sponsors, to postpone the event to 2021.
We deeply regret having to take this decision but we feel that in the current climate this was the only decision possible.
The new dates will be 5-6 March 2021.
All new deadlines have been updated in the website.


M.S. Aapro, CH  - J. Gligorov, FR


The main common feature of cancer cells is their ability to escape to homeostatic regulation mechanisms of living. In a sense giving them immortality, causing in the absence of treatment the death of the organism, which is their origin. The exponential knowledge of the biology of cancer and the phenomenal capacity of synthesis of new treatments and diagnostic tools have opened up the prospect of a precision medicine in oncology that requires regular and frequent updating of our knowledge.
This knowledge concerns both the intrinsic prognosis of the disease, as the prediction value of therapeutic approaches that in fact becomes increasingly “personalized”. This course aims to take stock of current and future tools that help us optimize the care of patients with breast cancer.

Learning Objectives

  • Improve breast cancer patients care: value and clinical utility of prediction of CT benefit for early stage breast cancer patients
  • Practicing through case discussions


 Under the auspices of




Matti Aapro, Clinique de Genolier, Breast Center, Genolier, CH
Fabrice André, Institut Gustave Roussy, Dept. of Medical Oncology, Villejuif, FR
Anna Batistatou, University of Ioannina, Faculty of Medicine, Ioannina, GR
Francesco Cognetti, Istituto Nazionale Tumori Regina Elena, Dipartimento di Oncologia Medica, Roma, IT
Joseph Gligorov, University Cancer Institute APHP.6 Sorbonne University, Breast Cancer Expert Center, Paris, FR
Susan Knox, Europa Donna - The European Breast Cancer Coalition, Milan, IT
Christos Markopoulos, Athens, GR
Riccardo Masetti, Università Cattolica di Roma, Oncology Dpt., Roma, IT
Belinda Nedjai, Queen Mary University of London, Wolfson Institute of Preventive Medicine - Centre for Cancer Prevention, London, GB
Frederique Penault Llorca, Centre Jean Perrin, Anatomopathology Dpt., Clermont-ferrand Cedex, FR
Giancarlo Pruneri, Fondazione IRCCS - Istituto Nazionale dei Tumori, Pathology Dpt., Milano, IT
Pascale Pujol, Centre Hospitalier Universitaire de Montpellier, Genetics Department, Montpellier Cedex5, FR
Elzbieta Senkus, Medical University of Gdansk, Dept. of Oncology and Radiotherapy, Gdansk, PL
Zsuzsanna Varga, University Hospital Zurich, Pathology Dept., Zurich, CH
Mark Verrill, Northern Centre for Cancer Care, Freeman Hospital, Medical Oncology Dept., Newcastle upon Tyne, GB

General information


Sharing Progress in Cancer Care
Piazza Indipendenza, 2
6500 Bellinzona – Switzerland

Luis Carvalho
Luis.carvalho@spcc.net  - Tel: +41 91 820 09 58


Mercure Roma West
Via Eroi di Cefalonia, 301
00128 Rome
Phone: +39 06 50 83 41 11
Website: https://bit.ly/2uLsKWL

CME Accreditation and Certificates

Participants will be entitled to receive  a certificate of attendance at the close of the event by completing the on-line evaluation questionnaire.

Application for CME recognition will be submitted to the Accreditation Council of Oncology in Europe (ACOE) and the European Accreditation Council for Continuing Medical Education (EACCME), an institution of the European Union of Medical Specialists (UEMS).

EACCME credits are recognised by the American Medical Association towards the Physician’s Recognition Award (PRA).

Information on the status of the applications can be obtained from the organising secretariat.


Sharing Progress in Cancer Care wishes to extend its appreciation to Exact Sciences and Pfizer for having granted their participation and support to the Course.

Travel Grant

Travel grants are made available on a competitive basis.
Full applications should be submitted by 29 November 2020 via website www.spcc.net
and include:
- Curriculum vitae including full affiliation, contact details and date of birth;
- Letter describing motivation for attending;
- Letter of endorsement by the Institute/Department director.

Travel grant recipients will receive a set amount to contribute to their travel expenses, whilst registration ad accommodation will be processed directly by SPCC.
The following amounts will be refunded by bank transfer after the Course:

The outcome of the application will be notified by 14 December 2020.



Terms and Conditions

All rates are quoted in Euro and include VAT.


• 2 nights accommodation at the venue
• Participation in all sessions and a copy of the Programme Book,
• Coffee breaks and lunches as indicated in the programme.

Cancellation should be notified to SPCC in writing. In case of cancellation without replacement, the fee less handling charges of EUR 100 will be refunded within two months from notification, provided that the cancellation is received by SPCC before 31 January 2021. Replacements will be possible till 7 February 2021.

Registration will be confirmed by e-mail.

The badge is the only official evidence of registration and should be worn at all times during the event. Loss of badge causes loss of registration.

The organisers bear no responsibility for untoward events in relation to the participation in the course. Participants are advised to take out their own personal and travel insurance.


05 March

9:00Welcome and introduction
Matti Aapro, CH - Joseph Gligorov, FR
9:15Optimize patient management in breast cancer: guiding adjuvant treatment decisions
Mark Verrill, GB
9:40Clinical utility of multigene assays in early breast cancer
 9:40Predictive tests
Christos Markopoulos, GR
 9:55Prognostic tests
Francesco Cognetti, IT
10:45Who to test with multigene assay: treatment algorithms – specific patient profiles (lobular; premenopausal CT decisions)
 10:45Clinical perspective
 11:00Next Generation Sequencing . The Pathology perspective
Anna Batistatou, GR
11:30Roundtable: Evidence based assessment of diagnostic tests: criteria for a health technology assessment – why outcomes of HTA decisions can be different…?
 11:30The French rationale
Pascale Pujol, FR
 11:40Why NICE accepted?
Mark Verrill, GB
 11:50Why German authorities accepted?
12:15The patient’s perspective: patient preferences, patient journey
Susan Knox, IT
14:15Group session: Patient Case discussion on multigene assays in early breast cancer: who to test and how to deal with the results?
  Case 1: 1 patient 29 years luminal pN0 with low risk signature results
  Case 2: 1 patient 73 years luminal pN1 with high risk signature results
  Case 3: 1 patient 45 years luminal pN0 with intermediate risk signature results
  Case 4: 1 patient 52 years luminal pN0 with intermediate risk signature
  Group 1
Panellists: Joseph Gligorov, FR - Riccardo Masetti, IT - Elzbieta Senkus, PL - Zsuzsanna Varga, CH
  Group 2
Panellists: Matti Aapro, CH - Christos Markopoulos, GR - Giancarlo Pruneri, IT
17:00Day's closure

06 March

8:30DNA Methylation
Belinda Nedjai, GB
9:00NGS impact or not in breast cancer
Fabrice André, FR
9:30Alpelisib what to test
Frederique Penault-Llorca, FR - Elzbieta Senkus, PL
10:00Parp inhibitors what to test
Pascale Pujol, FR
10:40Coffee break
11:00Immunotherapy: what to test
Francesco Cognetti, IT - Frederique Penault-Llorca, FR
11:40New definition of ASCO CAP HER-2 positivity
Joseph Gligorov, FR - Frederique Penault-Llorca, FR
Matti Aapro, CH - Joseph Gligorov, FR
12:35Lunch and departures